【2023-03 Plants】Essential Oil from Glossogyne tenuifolia Inhibits Lipopolysaccharide-Induced Inflammation-Associated Genes in Macro-Phage Cells via Suppression of NF-κB Signaling Pathway

【2023-03 Phytotherapy Research】Antcin A, a phytosterol regulates SARS‐CoV‐2 spike protein‐mediated metabolic ation in THP‐1 cells explored by the 1H‐NMR‐based metabolomics approach

【2022-12 Environmental Toxicology】Limonene protects human skin keratinocytes against UVB‐induced photodamage and photoaging by activating the Nrf2‐dependent antioxidant defense

【2022-06 Natural Products and Biotechnology】The Impact of Cold Acclimatization on Antioxidant Enzyme Activity of Vicia sativa L.

【2021-12 Plants】Anti-melanogenic Activity of Calocedrus formosana Wood Essential Oil and Its Chemical Composition Analysis

【2021-08 Plants】Antcins from Antrodia cinnamomea and Antrodia salmonea Inhibit Angiotensin-Converting Enzyme 2 (ACE2) in Epithelial Cells: Can Be Potential Candidates for the Development of SARS-CoV-2 Prophylactic Agents

【2020-11 Plants】Essential Oils of Alpinia nantoensis Retard Forskolin-Induced Melanogenesis via ERK1/2-Mediated Proteasomal Degradation of MITF

【2020-06 Plants】Geranium and Lemon Essential Oils and Their Active Compounds Downregulate Angiotensin-Converting Enzyme 2 (ACE2), a SARS-CoV-2 Spike Receptor-Binding Domain, in Epithelial Cells

【2020-01 Journal of Food and Drug Analysis】A mechanistic and empirical review of antcins, a new class of phytosterols of formosan fungi origin

【2020- Plants】The regulatory effects of a formulation of cinnamomum osmophloeum kaneh and taiwanofungus camphoratus on metabolic syndrome and the gut microbiome

【2019- Planta Medica】Antcin-A Modulates Epithelial-to-Mesenchymal Transition and Inhibits Migratory and Invasive Potentials of Human Breast Cancer Cells via p53-Mediated miR-200c Activation

【2019- Natural Product Communications】Dietary indigenous cinnamon (Cinnamomum osmophloeum) leaf powder reduces plasma lipid in hypercholesterolemia hamsters

【2019- Integrative Cancer Therapies】Ethanol Extracts of Dietary Herb, Alpinia nantoensis, Exhibit Anticancer Potential in Human Breast Cancer Cells

【2019- Carcinogenesis】MicroRNA-708 activation by glucocorticoid receptor agonists regulate breast cancer tumorigenesis and metastasis via downregulation of NF-κB signaling

【2018-11 Phytomedicine】trans-3-Methoxy-5-hydroxystilbene (MHS) from the rhizome of Alpinia nantonensis inhibits metastasis in human lung cancer cells

【2018- International Journal of Medicinal Mushrooms】Immunomodulatory effects of the stout camphor medicinal mushroom, taiwanofungus camphoratus (Agaricomycetes)–based health food product in mice

【2017-10 第32屆天然藥物國際研討會 The 32nd International Symposium on Natural Products】Antcin M Prevents Hyperglycemia-Accelerated Pre-Mature Senescence in Dermal Fibroblasts by Direct Activation of Nrf2 and SIRT-1 Genes

【2017- Oncotarget】Activation of Nrf2-mediated anti-oxidant genes by antrodin C prevents hyperglycemia-induced senescence and apoptosis in human endothelial cells

【2017- Medicinal and Aromatic Plants of the World】Antioxidant Properties of Antrodia cinnamomea: An Extremely Rare and Coveted Medicinal Mushroom Endemic to Taiwan

【2016- Fundamental Toxicological Sciences】In vitro and in vivo toxicological assessments of Antrodia cinnamomea health food product (Leader Antrodia cinnamomea Capsule)

【2016- Oncotarget】A steroid like phytochemical Antcin M is an anti-aging reagent that eliminates hyperglycemia-accelerated premature senescence in dermal fibroblasts by direct activation of Nrf2 and SIRT-1

【2016- Medicinal Plants - Recent Advances in Research and Development】Pharmacological applications of lucidone: A naturally occurring cyclopentenedione

【2015- Journal of Natural Medicines】2,3,5-Trimethoxy-4-cresol, an anti-metastatic constituent from the solid-state cultured mycelium of Antrodia cinnamomea and its mechanism

【2015- PLoS ONE】Antrodin C inhibits epithelial-to-mesenchymal transition and metastasis of breast cancer cells via suppression of Smad2/3 and β-catenin signaling pathways

【2015- Planta Medica】Bornyl cinnamate inhibits inflammation-associated gene expression in macrophage cells through suppression of nuclear factor-κB signaling pathway

【2015- Natural Product Communications】Effect of hinoki and meniki essential oils on human autonomic nervous activity and mood states

【2015- Toxicology Reports】Genotoxic, teratotoxic and oral toxic assessments of Antrodia cinnamomea health food product (Leader Deluxe Antrodia cinnamomea)

【2014- Food and Function】Antrodia camphorata induces G1 cell-cycle arrest in human premyelocytic leukemia (HL-60) cells and suppresses tumor growth in athymic nude mice

【2014- Food and Chemical Toxicology】Antrodia salmonea in submerged culture exhibits antioxidant activities in vitro and protects human erythrocytes and low-density lipoproteins from oxidative modification

【2014- Journal of Ethnopharmacology】Antrodia salmonea inhibits TNF-α-induced angiogenesis and atherogenesis in human endothelial cells through the down-regulation of NF-κB and up-regulation of Nrf2 signaling pathways

【2014- Toxicology and Applied Pharmacology】Humic acid in drinking well water induces inflammation through reactive oxygen species generation and activation of nuclear factor-κB/activator protein-1 signaling pathways: A possible role in atherosclerosis

【2014- Environmental and Molecular Mutagenesis】Induction of macrophage cell-cycle arrest and apoptosis by humic acid

【2014- International Journal of Polymeric Materials and Polymeric Biomaterials】PH-Sensitive hollow alginate-chitosan hydrogel beads for bitter gourd delivery

【2014- Journal of Ethnopharmacology】The anti-tumor activity of Antrodia salmonea in human promyelocytic leukemia (HL-60) cells is mediated via the induction of G1 cell-cycle arrest and apoptosis in vitro or in vivo

【2014- Oxidative Medicine and Cellular Longevity】Toona sinensis inhibits LPS-induced inflammation and migration in vascular smooth muscle cells via suppression of reactive oxygen species and NF-B signaling pathway

【2013- Evidence-based Complementary and native Medicine】Antcin C from Antrodia cinnamomea protects liver cells against free radical-induced oxidative stress and apoptosis in vitro and in vivo through nrf2-dependent mechanism

【2013- BioFactors】In vitro and in vivo studies disclosed the depigmenting effects of gallic acid: A novel skin lightening agent for hyperpigmentary skin diseases

【2013- Food and Chemical Toxicology】Lucidone protects human skin keratinocytes against free radical-induced oxidative damage and inflammation through the up-regulation of HO-1/Nrf2 antioxidant genes and down-regulation of NF-κB signaling pathway

【2013- Journal of Ethnopharmacology】The anti-cancer activity of Antrodia camphorata against human ovarian carcinoma (SKOV-3) cells via modulation of HER-2/neu signaling pathway

【2013- Food Chemistry】Toona sinensis and its major bioactive compound gallic acid inhibit LPS-induced inflammation in nuclear factor-κB transgenic mice as uated by in vivo bioluminescence imaging

【2012-02 Targeting New Pathways and Cell Death in Breast Cancer】Multiple Molecular Targets of Antrodia camphorata: A Suitable Candidate for Breast Cancer Chemoprevention

【2012- Journal of Agricultural and Food Chemistry】Antioxidant and anti-inflammatory potential of hesperetin metabolites obtained from hesperetin-administered rat serum: An ex vivo approach

【2012- Molecular Cancer Research】Clinical significance of increased guanine nucleotide exchange factor Vav3 expression in human gastric cancer

【2012- Food and Chemical Toxicology】Ellagic acid protects human keratinocyte (HaCaT) cells against UVA-induced oxidative stress and apoptosis through the upregulation of the HO-1 and Nrf-2 antioxidant genes

【2012- Toxicology in Vitro】Hepatoprotective effect of lucidone against alcohol-induced oxidative stress in human hepatic HepG2 cells through the up-regulation of HO-1/Nrf-2 antioxidant genes

【2012- Food and Chemical Toxicology】In vitro and in vivo activity of gallic acid and Toona sinensis leaf extracts against HL-60 human premyelocytic leukemia

【2012- Evidence-based Complementary and native Medicine】Inhibition of cell growth and induction of apoptosis by Antrodia camphorata in HER-2/neu-overexpressing breast cancer cells through the induction of ROS, depletion of HER-2/neu, and disruption of the PI3K/Akt signaling pathway

【2012- Evidence-based Complementary and native Medicine】The antitumor activity of Antrodia camphorata in melanoma cells: Modulation of Wnt/β-catenin signaling pathways

【2012- Journal of Agricultural and Food Chemistry】The chalcone flavokawain b induces G 2/M cell-cycle arrest and apoptosis in human oral carcinoma HSC-3 Cells through the intracellular ROS generation and downregulation of the Akt/p38 MAPK signaling pathway

【2011- Journal of Ethnopharmacology】Antioxidant activities of aqueous leaf extracts of Toona sinensis on free radical-induced endothelial cell damage